Truth: Only physical trauma to the brain can cause holes
Drug use ma not put holes in your brain but it can make long lasting changes. Drug use alters the level of neurotransmitters that the brain releases because the drug makes the brain produce an overwhelming amount, so much that it eventually stops producing them on its own. There is still a lot f controversy concerning the long lasting effects of drugs and which ones cause the most harm but researchers are certain that they do not cause holes.